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Aging and Health

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ISBN: 9783318027297 9783318027303 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103014
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:22:14
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Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging.

Self-Reported Population Health: An International Perspective based on EQ-5D

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ISBN: 9789400775954 9789400775961 Year: Pages: 212 DOI: 10.1007/978-94-007-7596-1 Language: English
Publisher: Springer
Subject: Public Health --- Biotechnology --- Pharmacy and materia medica --- Medicine (General)
Added to DOAB on : 2014-07-25 14:27:36
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The EQ-5D instrument, as a standardized, cross-culturally validated measure of self-assessed health has a hugely important role in understanding population health within and across countries. Over the past two decades a wealth of international population health survey data have been accumulated by the EuroQol Group from research conducted in many countries across four continents. One of the success factors of the EQ-5D instruments has been the easy availability of national or international sets of EQ-5D data, as well as clear explanations and guidance for users. There is an unmet need to produce a comprehensive book that captures up-to-date and expanded information of EQ-5D self-reported health and index values. EQ-5D population norms and cross-country analyses are provided from representative national surveys of 20 countries and additional regional surveys. This book will be a must for those who believe that how people report and value health is very important.

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