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Synthetic biology applications in industrial microbiology

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193424 Year: Pages: 129 DOI: 10.3389/978-2-88919-342-4 Language: English
Publisher: Frontiers Media SA
Subject: Environmental Sciences --- Biotechnology --- General and Civil Engineering --- Microbiology --- Science (General)
Added to DOAB on : 2016-03-10 08:14:32
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Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.

Sugar, Steam and Steel: The Industrial Project in Colonial Java, 1830-1850

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ISBN: 9781922064998 Year: Pages: 322 DOI: 10.20851/steam-and-steel Language: English
Publisher: University of Adelaide Press
Subject: History --- Migration
Added to DOAB on : 2014-12-19 00:53:15
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Sugar, Steam and Steel is about cane sugar and the transformation of an Indonesian island into the â Oriental Cubaâ during the middle decades of the nineteenth century. Between the 1830s and the 1880s, sweetener manufacture in Dutch-controlled Java â the crown jewel of the erstwhile Netherlands Indies â drew decisively away in matters of technology and sugar science from other Asian centres of production which had once equaled or, more often, surpassed it in terms of both output and know-how. Along with its larger and altogether more famous Caribbean counterpart, Javaâ s industry came to occupy a position at the apex of the trade in what had become by this date a key global commodity.

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