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The Amygdala - A Discrete Multitasking Manager

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ISBN: 9789535109082 9789535142621 Year: Pages: 420 DOI: 10.5772/2973 Language: English
Publisher: IntechOpen
Subject: Neurology
Added to DOAB on : 2019-10-03 09:47:09

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Abstract

Among the components of the limbic system, the amygdala is a fascinating structure that is involved in the processes of liking and disliking and in the ways our emotions drive our actions and affect the strength of our memories. Combined with new conceptual breakthroughs, the very latest data obtained by leading world experts in amygdala function that are reviewed in this book have helped to understand how the amygdala contribute to these processes and also to a variety of neurological and neuropsychiatric pathologies. Of course, due to the rate of research advancement, all the chapters presented here correspond to precise questions addressed by experts using highly specific techniques. Therefore, each chapter should be viewed as pieces of a puzzle that represent all the different research areas that have to be taken into consideration in discussing the role of the amygdala in emotion and memory. Although the primary goal of this book is to inform experts and newcomers of some of the latest data in the field of brain structures involved in mechanisms underlying emotional learning and memory, we hope it will also help to stimulate discussion on the functional role of the amygdala and connected brain structures in these mechanisms.

Amyotrophic Lateral Sclerosis

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ISBN: 9789533078069 Year: Pages: 740 DOI: 10.5772/1054 Language: English
Publisher: IntechOpen
Subject: Physiology
Added to DOAB on : 2019-10-03 07:51:48

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Though considerable amount of research, both pre-clinical and clinical, has been conducted during recent years, Amyotrophic Lateral Sclerosis (ALS) remains one of the mysterious diseases of the 21st century. Great efforts have been made to develop pathophysiological models and to clarify the underlying pathology, and with novel instruments in genetics and transgenic techniques, the aim for finding a durable cure comes into scope. On the other hand, most pharmacological trials failed to show a benefit for ALS patients. In this book, the reader will find a compilation of state-of-the-art reviews about the etiology, epidemiology, and pathophysiology of ALS, the molecular basis of disease progression and clinical manifestations, the genetics familial ALS, as well as novel diagnostic criteria in the field of electrophysiology. An overview over all relevant pharmacological trials in ALS patients is also included, while the book concludes with a discussion on current advances and future trends in ALS research.

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