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HIV Infection in the Era of Highly Active Antiretroviral Treatment and Some of Its Associated Complications

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ISBN: 9789533077017 Year: Pages: 224 DOI: 10.5772/1752 Language: English
Publisher: IntechOpen
Subject: Internal medicine
Added to DOAB on : 2019-10-03 07:51:48

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Human immunodeficiency virus (HIV) infection is a complex illness affecting the immune system. Acquired immunodeficiency syndrome (AIDS) is an advanced form of HIV infection in which the patient has developed opportunistic infections or certain types of cancer and/or the CD4+ T cell count has dropped below 200/μL. More than 40 million persons around the world are infected with HIV, with approximately 14,000 new infections every day. The disease causes 3 million deaths worldwide each year, 95% of them in developing countries. Optimal management of human immunodeficiency virus requires strict adherence to highly active antiretroviral treatment (HAART) regimens, but the complexity of these regimens (e.g., pill burden, food requirements, drug interactions, and severe adverse effects) limits effective treatment. However, more patients with HIV are surviving longer today because of these drugs. This allows further study of commonly associated adverse effects. These may affect all body systems and range from serious toxicities to uncomfortable but manageable events. This book reviews some of HAART-related metabolic and neurological complications.

Non-Flavivirus Encephalitis

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ISBN: 9789533077208 Year: Pages: 374 DOI: 10.5772/1740 Language: English
Publisher: IntechOpen
Subject: Internal medicine
Added to DOAB on : 2019-10-03 09:47:08

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This book covers the different aspects of non-flavivirus encephalitises of different ethiology. The first section of the book considers general problems of epidemiology such as study of zoonotic and animal vectors of encephalitis causative agents and methods and approaches for encephalitis zoonoses investigations. The members of different virus species are known to be the causative agents of encephalitis, so the second section of the book is devoted to these viral pathogens, their epidemiology, pathology, diagnostics and molecular mechanisms of encephalitis development by such viruses as HIV/SIV, herpes simplex virus type 1 and equine herpesvirus 9, measles virus, coronaviruses, alphaviruses and rabies virus. The next section of the book concerns the study of protozoan pathogens such as toxoplasma and amoebae. The last section of the book is devoted to multicellular pathogen as human Filaria Loa Loa - a filarial worm restricted to the West Africa.

Regenerative Medicine and Tissue Engineering - Cells and Biomaterials

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ISBN: 9789533076638 Year: Pages: 604 DOI: 10.5772/837 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
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Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration.

Advances in Regenerative Medicine

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ISBN: 9789533077321 Year: Pages: 418 DOI: 10.5772/1294 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
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Even if the origins of regenerative medicine can be found in Greek mythology, as attested by the story of Prometheus, the Greek god whose immortal liver was feasted on day after day by Zeus' eagle; many challenges persist in order to successfully regenerate lost cells, tissues or organs and rebuild all connections and functions. In this book, we will cover a few aspects of regenerative medicine highlighting major advances and remaining challenges in cellular therapy and tissue/organ engineering.

Applied Tissue Engineering

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ISBN: 9789533076898 Year: Pages: 98 DOI: 10.5772/2630 Language: English
Publisher: IntechOpen
Subject: Medicine (General)
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Tissue engineering, which aims at regenerating new tissues, as well as substituting lost organs by making use of autogenic or allogenic cells in combination with biomaterials, is an emerging biomedical engineering field. There are several driving forces that presently make tissue engineering very challenging and important: 1) the limitations in biological functions of current artificial tissues and organs made from man-made materials alone, 2) the shortage of donor tissue and organs for organs transplantation, 3) recent remarkable advances in regeneration mechanisms made by molecular biologists, as well as 4) achievements in modern biotechnology for large-scale tissue culture and growth factor production. This book was edited by collecting all the achievement performed in the laboratory of oral and maxillofacial surgery and it brings together the specific experiences of the scientific community in these experiences of our scientific community in this field as well as the clinical experiences of the most renowned experts in the fields from all over Nagoya University. The editors are especially proud of bringing together the leading biologists and material scientists together with dentist, plastic surgeons, cardiovascular surgery and doctors of all specialties from all department of the medical school of Nagoya University. Taken together, this unique collection of world-wide expert achievement and experiences represents the current spectrum of possibilities in tissue engineered substitution.

Modern Arthroscopy

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ISBN: 9789533077710 Year: Pages: 314 DOI: 10.5772/1149 Language: English
Publisher: IntechOpen
Subject: Surgery
Added to DOAB on : 2019-10-03 07:51:48

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Modern Arthroscopy will assist practitioners to stay current in the rapidly changing field of arthroscopic surgery. The chapters in this book were written by a panel of international experts in the various disciplines of arthroscopy. The goals of this text are to present the classical techniques and teachings in the fields of Orthopaedics and Dentistry, but also to include new, cutting-edge applications of arthroscopy, such as temporomandibular arthroscopy and extra-articular arthroscopy of the knee, just to name a few. We hope Modern Arthroscopy becomes a core reference for your arthroscopic surgery practice.

Implant Dentistry - A Rapidly Evolving Practice

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ISBN: 9789533076584 Year: Pages: 558 DOI: 10.5772/706 Language: English
Publisher: IntechOpen
Subject: Dentistry
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Implant dentistry has come a long way since Dr. Branemark introduced the osseointegration concept with endosseous implants. The use of dental implants has increased exponentially in the last three decades. As implant treatment became more predictable, the benefits of therapy became evident. The demand for dental implants has fueled a rapid expansion of the market. Presently, general dentists and a variety of specialists offer implants as a solution to partial and complete edentulism. Implant dentistry continues to evolve and expand with the development of new surgical and prosthodontic techniques. The aim of Implant Dentistry - A Rapidly Evolving Practice, is to provide a comtemporary clinic resource for dentists who want to replace missing teeth with dental implants. It is a text that relates one chapter to every other chapter and integrates common threads among science, clinical experience and future concepts. This book consists of 23 chapters divided into five sections. We believe that, Implant Dentistry: A Rapidly Evolving Practice, will be a valuable source for dental students, post-graduate residents, general dentists and specialists who want to know more about dental implants.

Non-Viral Gene Therapy

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ISBN: 9789533075389 Year: Pages: 708 DOI: 10.5772/1010 Language: English
Publisher: IntechOpen
Subject: Genetics
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This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.

Healers on the colonial market; Native doctors and midwives in the Dutch East Indies

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Book Series: Verhandelingen van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde ISBN: 9789067183826 9789004253575 Year: Volume: 276 Pages: X, 376 DOI: 10.26530/OAPEN_400271 Language: English
Publisher: Brill Grant: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Subject: Social Sciences
Added to DOAB on : 2012-04-11 23:18:40
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Healers on the colonial market is one of the few studies on the Dutch East Indies from a postcolonial perspective. It provides an&#xD;enthralling addition to research on both the history of the Dutch&#xD;East Indies and the history of colonial medicine. This book will be&#xD;of interest to historians, historians of science and medicine, and&#xD;anthropologists.&#xD;&#xD;How successful were the two medical training programmes&#xD;established in Jakarta by the colonial government in 1851? One&#xD;was a medical school for Javanese boys, and the other a school&#xD;for midwives for Javanese girls, and the graduates were supposed&#xD;to replace native healers, the dukun. However, the indigenous&#xD;population was not prepared to use the services of these doctors and&#xD;midwives. Native doctors did in fact prove useful as vaccinators&#xD;and assistant doctors, but the school for midwives was closed in&#xD;1875. Even though there were many horror stories of mistakes made&#xD;during dukun-assisted deliveries, the school was not reopened, and&#xD;instead a handful of girls received practical training from European&#xD;physicians. Under the Ethical Policy there was more attention for&#xD;the welfare of the indigenous population and the need for doctors&#xD;increased. More native boys received medical training and went to&#xD;work as general practitioners. Nevertheless, not everybody accepted&#xD;these native doctors as the colleagues of European physicians.&#xD;&#xD;Liesbeth Hesselink (1943) received a PhD in the history of medicine&#xD;from the University of Amsterdam in 2009. She has had a career in&#xD;education and in politics. In addition she has published articles on&#xD;prostitution and the medical history of the Dutch East Indies.

Acute Phase Proteins - Regulation and Functions of Acute Phase Proteins

Author:
ISBN: 9789533072524 Year: Pages: 382 DOI: 10.5772/756 Language: English
Publisher: IntechOpen
Subject: Microbiology
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The two volumes of Acute Phase Proteins book consist of chapters that give a large panel of fundamental and applied knowledge on one of the major elements of the inflammatory process during the acute phase response, i.e., the acute phase proteins expression and functions that regulate homeostasis. We have organized this book in two volumes - the first volume, mainly containing chapters on structure, biology and functions of APP, the second volume discussing different uses of APP as diagnostic tools in human and veterinary medicine.

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