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Genome Informatics 2009:Genome Informatics Series Vol. 22

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Book Series: Genome Informatics Series ISBN: 9781848165786 Year: Pages: 228 DOI: 10.1142/p718 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 04:29:21

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This volume contains 17 peer-reviewed papers based on the presentations at the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) held at the Life Science Engineering Building of Boston University from July 27 to 29, 2009. This workshop started in 2001 as a platform for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following institutions and programs:Boston University Graduate Program in BioinformaticsCharité – Universitätsmedizin BerlinFreie Universität BerlinGlobal COE Program — Center of Education and Research for Advanced Genome-Based Medicine, University of TokyoThe International Research Training Group (IRTG) Genomics and Systems Biology of Molecular NetworksInternational Research and Training Program on Bioinformatics and Systems Biology, Kyoto University Bioinformatics CenterMax-Delbrück Center for Molecular Medicine in BerlinMax Planck Institute for Molecular Genetics in BerlinMax Planck Institute of Molecular Plant Physiology in Potsdam

Genome Informatics 2009:Genome Informatics Series Vol. 23

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Book Series: Genome Informatics Series ISBN: 9781848165632 Year: Pages: 240 DOI: 10.1142/p715 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 04:35:35

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This volume contains papers presented at the 20th International Conference on Genome Informatics (GIW 2009) held at the Pacifico Yokohama, Japan from December 14 to 16, 2009. The GIW Series provides an international forum for the presentation and discussion of original research papers on all aspects of bioinformatics, computational biology and systems biology. Its scope includes biological sequence analysis, protein structure prediction, genetic regulatory networks, bioinformatic algorithms, comparative genomics, and biomolecular data integration and analysis. Boasting a history of 20 years, GIW is the longest-running international bioinformatics conference.A total of 18 contributed papers were selected for presentation at GIW 2009 and for inclusion in this book. In addition, this book contains abstracts from the five invited speakers: Sean Eddy (HHMI's Janelia Farm, USA), Minoru Kanehisa (Kyoto University, Japan), Sang Yup Lee (KAIST, Korea), Hideyuki Okano (Keio University, Japan) and Mark Ragan (University of Queensland, Australia).

Biological Information:New Perspectives

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ISBN: 9789814508728 Year: Pages: 584 DOI: 10.1142/8818 Language: English
Publisher: World Scientific Publishing Co.
Subject: Technology (General)
Added to DOAB on : 2016-01-19 03:49:23
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In the spring of 2011, a diverse group of scientists gathered at Cornell University to discuss their research into the nature and origin of biological information. This symposium brought together experts in information theory, computer science, numerical simulation, thermodynamics, evolutionary theory, whole organism biology, developmental biology, molecular biology, genetics, physics, biophysics, mathematics, and linguistics. This volume presents new research by those invited to speak at the conference.The contributors to this volume use their wide-ranging expertise in the area of biological information to bring fresh insights into the many explanatory difficulties associated with biological information. These authors raise major challenges to the conventional scientific wisdom, which attempts to explain all biological information exclusively in terms of the standard mutation/selection paradigm.Several clear themes emerged from these research papers: 1) Information is indispensable to our understanding of what life is; 2) Biological information is more than the material structures that embody it; 3) Conventional chemical and evolutionary mechanisms seem insufficient to fully explain the labyrinth of information that is life. By exploring new perspectives on biological information, this volume seeks to expand, encourage, and enrich research into the nature and origin of biological information.Contents:Session One — Information Theory & Biology: Introductory Comments (Robert J Marks II):Biological Information — What is It? (Werner Gitt, Robert Compton and Jorge Fernandez)A General Theory of Information Cost Incurred by Successful Search (William A Dembski, Winston Ewert and Robert J Marks II)Pragmatic Information (John W Oller, Jr)Limits of Chaos and Progress in Evolutionary Dynamics (William F Basener)Tierra: The Character of Adaptation (Winston Ewert, William A Dembski and Robert J Marks II)Multiple Overlapping Genetic Codes Profoundly Reduce the Probability of Beneficial Mutation (George Montañez, Robert J Marks II, Jorge Fernandez and John C Sanford)Entropy, Evolution and Open Systems (Granville Sewell)Information and Thermodynamics in Living Systems (Andy C McIntosh)Session Two — Biological Information and Genetic Theory: Introductory Comments (John C Sanford):Not Junk After All: Non-Protein-Coding DNA Carries Extensive Biological Information (Jonathan Wells)Can Purifying Natural Selection Preserve Biological Information? (Paul Gibson, John R Baumgardner, Wesley H Brewer and John C Sanford)Selection Threshold Severely Constrains Capture of Beneficial Mutations (John C Sanford, John R Baumgardner and Wesley H Brewer)Using Numerical Simulation to Test the “Mutation-Count” Hypothesis (Wesley H Brewer, John R Baumgardner and John C Sanford)Can Synergistic Epistasis Halt Mutation Accumulation? Results from Numerical Simulation (John R Baumgardner, Wesley H Brewer and John C Sanford)Computational Evolution Experiments Reveal a Net Loss of Genetic Information Despite Selection (Chase W Nelson and John C Sanford)Information Loss: Potential for Accelerating Natural Genetic Attenuation of RNA Viruses (Wesley H Brewer, Franzine D Smith and John C Sanford)DNA.EXE: A Sequence Comparison between the Human Genome and Computer Code (Josiah Seaman)Biocybernetics and Biosemiosis (Donald Johnson)Session Three — Theoretical Molecular Biology: Introductory Comments (Michael J Behe):An Ode to the Code: Evidence for Fine-Tuning in the Standard Codon Table (Jed C Macosko and Amanda M Smelser)A New Model of Intracellular Communication Based on Coherent, High-Frequency Vibrations in Biomolecules (L Dent)Getting There First: An Evolutionary Rate Advantage for Adaptive Loss-of-Function Mutations (Michael J Behe)The Membrane Code: A Carrier of Essential Biological Information That is Not Specified by DNA and is Inherited Apart from It (Jonathan Wells)Explaining Metabolic Innovation: Neo-Darwinism Versus Design (Douglas D Axe and Ann K Gauger)Session Four — Biological Information and Self-Organizational Complexity Theory: Introductory Comments (Bruce L Gordon):Evolution Beyond Entailing Law: The Roles of Embodied Information and Self Organization (Stuart Kauffman)Towards a General Biology: Emergence of Life and Information from the Perspective of Complex Systems Dynamics (Bruce H Weber)Readership: Academics, researchers, postgraduates and advanced undergraduates in bioinformatics. Biologists, mathematicians/statisticians, physicists and computer scientists.

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