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Sexual Reproduction in Animals and Plants

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ISBN: 9784431545880 9784431545897 Year: Pages: 480 DOI: 10.1007/978-4-431-54589-7 Language: English
Publisher: Springer
Subject: Biotechnology --- Pharmacy and materia medica --- Manufactures --- Biology
Added to DOAB on : 2014-03-05 12:56:57
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This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.

Innovative Medicine: Basic Research and Development

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ISBN: 9784431556503 9784431556510 Year: Pages: 339 DOI: 10.1007/978-4-431-55651-0 Language: English
Publisher: Springer
Subject: Medicine (General)
Added to DOAB on : 2016-06-30 12:46:49
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This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Make Life Visible

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ISBN: 9789811379086 Year: Pages: 292 DOI: 10.1007/978-981-13-7908-6 Language: English
Publisher: Springer
Subject: Biology --- Neurology --- Medicine (General)
Added to DOAB on : 2020-02-04 11:21:23
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This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in the broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license. ;

Bioimage Data Analysis Workflows

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Book Series: Learning Materials in Biosciences ISBN: 9783030223861 Year: Pages: 170 DOI: 10.1007/978-3-030-22386-1 Language: English
Publisher: Springer
Subject: Biology --- Medicine (General)
Added to DOAB on : 2020-02-04 11:21:06
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This Open Access textbook provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python. Besides gaining knowhow on algorithm usage, readers will learn how to create an analysis pipeline by scripting language; these skills are important in order to document reproducible image analysis workflows. The textbook is chiefly intended for advanced undergraduates in the life sciences and biomedicine without a theoretical background in data analysis, as well as for postdocs, staff scientists and faculty members who need to perform regular quantitative analyses of microscopy images.

A Time for Metabolism and Hormones

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Book Series: Research and Perspectives in Endocrine Interactions ISSN: 1861-2253 ISBN: 9783319270685 9783319270692 Year: Pages: 132 DOI: 10.1007/978-3-319-27069-2 Language: English
Publisher: Springer
Subject: Internal medicine
Added to DOAB on : 2016-12-20 11:46:51
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Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Evolutionary Genomics

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Book Series: Methods in Molecular Biology ISBN: 9781493990740 Year: Pages: 780 DOI: 10.1007/978-1-4939-9074-0 Language: English
Publisher: Springer
Subject: Biology
Added to DOAB on : 2020-01-29 11:21:11
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This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. Authoritative and comprehensive, Evolutionary Genomics: Statistical and Computational Methods, Second Edition aims to serve both novices in biology with strong statistics and computational skills, and molecular biologists with a good grasp of standard mathematical concepts, in moving this important field of study forward.

Bird Species

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Book Series: Fascinating Life Sciences ISBN: 9783319916897 Year: Pages: 266 DOI: 10.1007/978-3-319-91689-7 Language: English
Publisher: Springer
Subject: Zoology --- Biology
Added to DOAB on : 2020-02-05 11:21:16
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The average person can name more bird species than they think, but do we really know what a bird “species” is? This open access book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of birds – with their environment and other birds. Lastly, it shows imminent threats to birds in the Anthropocene, the era of global human impact. Although it seemed to be easy to define bird species, the advent of modern methods has challenged species definition and led to a multidisciplinary approach to classifying birds. One outstanding new toolbox comes with the more and more reasonably priced acquisition of whole-genome sequences that allow causative analyses of how bird species diversify. Speciation has reached a final stage when daughter species are reproductively isolated, but this stage is not easily detectable from the phenotype we observe. Culturally transmitted traits such as bird song seem to speed up speciation processes, while another behavioral trait, migration, helps birds to find food resources, and also coincides with higher chances of reaching new, inhabitable areas. In general, distribution is a major key to understanding speciation in birds. Examples of ecological speciation can be found in birds, and the constant interaction of birds with their biotic environment also contributes to evolutionary changes. In the Anthropocene, birds are confronted with rapid changes that are highly threatening for some species. Climate change forces birds to move their ranges, but may also disrupt well-established interactions between climate, vegetation, and food sources. This book brings together various disciplines involved in observing bird species come into existence, modify, and vanish. It is a rich resource for bird enthusiasts who want to understand various processes at the cutting edge of current research in more detail. At the same time it offers students the opportunity to see primarily unconnected, but booming big-data approaches such as genomics and biogeography meet in a topic of broad interest. Lastly, the book enables conservationists to better understand the uncertainties surrounding “species” as entities of protection.

Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates

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ISBN: 9783319137544 9783319137551 Year: Pages: 246 DOI: 10.1007/978-3-319-13755-1 Language: English
Publisher: Springer
Subject: Therapeutics --- Biotechnology --- Microbiology
Added to DOAB on : 2016-04-12 15:59:14
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This is the first book on ranaviruses. Ranaviruses are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. They have caused mass die-offs of ectothermic vertebrates in wild and captive populations around the globe. There is evidence that this pathogen is emerging and responsible for population declines in certain locations. Considering that amphibians and freshwater turtles are suitable hosts and the most imperiled vertebrate taxa in the world, ranaviruses can have significant impacts on biodiversity and ecosystem function. Additionally, many fish that are raised in aquaculture facilities and traded internationally are suitable hosts; thus, the potential economic impact of ranaviruses is significant. Ranaviruses also serve as a model for replication and gene function of large double-stranded DNA viruses. There is an urgent need to assemble the contemporary information on ranaviruses and provide guidance on how to assess their threats in populations. Through the Global Ranavirus Consortium, 24 experts from six countries were organize to write this volume, the first book on ranaviruses. The book begins with a discussion on the global extent of ranaviruses, case histories of infection and disease in ectothermic vertebrates, and current phylogeny. Basic principles of ranavirus ecology and evolution are covered next, with a focus on host-pathogen interactions and how the virus emerges in its environment. There are two chapters that will discuss the molecular biology of ranaviruses, host response to infection, and the genes responsible for immune system evasion. One chapter establishes standards for testing for infection and diagnosing ranaviral disease. The book ends by providing guidance on how to design ranavirus surveillance studies and analyze data to determine risk, and discussing the role of the Global Ranavirus Consortium in organizing research and outreach activities.

High Density Lipoproteins: From Biological Understanding to Clinical Exploitation

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Book Series: Handbook of Experimental Pharmacology ISSN: 01712004 ISBN: 9783319096643 9783319096650 Year: Volume: 224 Pages: 694 DOI: 10.1007/978-3-319-09665-0 Language: English
Publisher: Springer
Subject: Manufactures --- Electrical and Nuclear Engineering --- Chemical Technology --- Business and Management --- Biotechnology --- Therapeutics --- Medicine (General)
Added to DOAB on : 2015-07-20 15:18:00
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n this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation.The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.

Impacts of the Fukushima Nuclear Accident on Fish and Fishing Grounds

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ISBN: 9784431555360 9784431555377 Year: Pages: 238 DOI: 10.1007/978-4-431-55537-7 Language: English
Publisher: Springer
Subject: Aquaculture and Fisheries --- Business and Management --- Chemical Engineering
Added to DOAB on : 2016-06-27 16:32:42
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This book presents the results from the Japanese Fisheries Research Agency’s 3-year intensive monitoring of radionuclides in a variety of fish, plankton, benthos, and their living environments after the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in March 2011. The book reveals the dynamics of contamination processes in marine and freshwater fish, mediated by the contamination of water, sediments, and food organisms; it also clarifies the mechanisms by which large variations in the level of contamination occurs among individual fish. Most importantly, the book includes a large amount of original measurement data collected in situ and for the first time assesses diffusion of radiocesium across the Pacific using both in situ data and a numerical simulation model. Also introduced are several new approaches to evaluate the impact of the release of radionuclides, including the measurement of radiation emission from an otolith section to identify the main period of contamination in fish. The FNPP accident represents a rare instance where the environmental radioactivity level was elevated steeply through atmospheric fallout and direct discharge of radioactive water into the sea over a short period of time. Replete with precise scientific data, this book will serve as an important resource for research in fields such as fishery science, oceanography, ecology, and environmentology, and also as a solid basis for protecting fisheries from damage resulting from harmful rumors among the general public.

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