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Plant Medicines for Clinical Trial

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ISBN: 9783038970231 9783038970248 Year: Pages: X, 124 Language: english
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Therapeutics
Added to DOAB on : 2018-08-09 10:40:08
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Plant medicines are the original medicines that humans have always used. Many people continue to use plant medicines today including teas, coffee, chocolate, ginger, and other medicines. Traditional medicine is based on plant medicines and is the primary form of medicine for many people throughout the world. The current volume discusses traditional medicines and presents various plant medicines that could be tested in clinical trials. Modern medicine continues to use many drugs that are derived from plants. The current work has much to teach modern medicine about the treatment of several diseases. Traditional healers have used plant medicines to treat psychiatric and other conditions that modern medicine struggles with. Safety issues are always a concern with plant medicines, especially allergies to plant medicines. Clinical trials must be conducted with plant medicines to help bring these traditional treatments into use by modern medicine.

Roles of NF-κB in Cancer and Their Therapeutic Approaches

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ISBN: 9783038971177 9783038971184 Year: Pages: X, 330 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Oncology --- Biology
Added to DOAB on : 2018-08-15 10:52:09
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Although mortality rates have declined in recent years, the majority of cancers are still difficult to treat and the medical need for better cancer treatment is evident. The current anticancer armamentarium includes many active agents that are applied across tumor types. However, most of these broadly-active anticancer drugs have a small therapeutic index and barely discriminate between malignant and normal cells. In recent years the focus has shifted to the development of rationally designed, molecularly-targeted therapy for the treatment of a specific cancer, therefore offering the promise of greater specificity coupled with reduced systemic toxicity. NF-kB transcription factor family as emerged as such a promising target for cancer therapy. This Special Issue will explore the routes from NF-kB basic research, cancer research and oncogenomics into the development of NF-kB-based cancer therapeutics and biomarkers.We invite research and review papers in any area of the NF-kB field that are related, but not limited to, fundamental understanding of NF-kB signaling pathways, gene expression profiling, epigenetic regulation, diagnostic, prognostic and pharmacogenomic biomarkers, molecular targets driving the progression of human cancers, cancer drug development on these targets, clinical trial with new agents, and validation in animal models.We hope that this Special Issue reflects the exciting era that we are living in with respect to the field of NF-kB and its applications in cancer research.

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MDPI - Multidisciplinary Digital Publishing Institute (2)


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english (2)


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2018 (2)