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Omega-3 Fatty Acids in Health and Disease

ISBN: 9783038422723 9783038422730 Year: Pages: XII, 312 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2016-11-11 19:02:10
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The role of major dietary omega-3 fatty acids (Ω-3; α-linolenic acid, eicosapentaenoic acid and docosahexaenoic acid) in human health has generated enormous scientific interest and many controversies in recent years. Due to a growing number of studies with conflicting or even negative clinical results, the former “hype” of Ω-3 thought to be beneficial in many aspects of human health regardless of the physiological and clinical preconditions is now being critically re-evaluated, especially with respect to the potential role of Ω-3 fatty acid supplementation in preventing a variety of diseases and clinical conditions. This critical view reflects the complex interaction of Ω-3 with cell membranes and their integrated proteins mediating signal transduction, transport systems, and other processes. Moreover, Ω-3 are precursors of bioactive metabolites, such as eicosanoids, lipoxins, resolvins, protectins, maresins, and nitrolipids that influence several physiological and pathophysiological processes and their full spectrum of effects are only beginning to be defined. Finally, physiological and pathophysiological conditions as well as concomitant pharmacological treatments may influence the specific and non-specific actions of Ω-3 supplementation.This Special Issue of the Journal of Clinical Medicine will emphasize the role and biological interactions of Ω-3 with regard to cancer, psychiatric disorders, metabolic disorders and nutrition and will also reflect on some basic molecular and cellular mechanisms.

Acupuncture – Basic Research and Clinical Application

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ISBN: 9783038972341 9783038972358 Year: Pages: 170 DOI: 10.3390/books978-3-03897-235-8 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Therapeutics
Added to DOAB on : 2018-10-09 11:13:34
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This book focuses on the investigation, development, and modernization of acupuncture in basic research settings as well as in clinical applications. The book contains 13 chapters reporting the latest evidence-based results of acupuncture research and exploring acupuncture in general. Altogether, 44 authors from all over the world contributed to this book.

New Research in Obsessive-Compulsive Disorder and Major Depression

Authors: ---
ISBN: 9783039210909 / 9783039210916 Year: Pages: 102 DOI: 10.3390/books978-3-03921-091-6 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology
Added to DOAB on : 2019-06-26 08:44:07
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Major depression and obsessive–compulsive disorder (OCD) are now recognized among the most frequent psychiatric disorders, affecting 16–17% and 2–3% of the general population, respectively. They are commonly characterized by: i) a high level of psychiatric and somatic comorbidities; ii) a recurrence or chronic profile; and iii) a negative impact on daily functions, thereby leading to a profound impairment of quality of life. Despite significant advances in pharmacological and psychological therapies over the last decades, unsuccessful responses to standard treatment strategies are classically observed in approximately 20–30% of cases. Therefore, there is a significant need for improving the pathophysiological knowledge through a better identification of environmental, clinical, psychological, genetic, anatomical, and biological determinants, specifically implied in the development, the phenotypic expression, and the relapsing course and/or contributing to the therapeutic failure in major depression and OCD. We are convinced that this research approach is particularly relevant providing critical support for the promotion of innovative treatment alternatives potentially useful for the management of resistant forms of major depression and OCD.

The Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of Development

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ISBN: 9783039217021 / 9783039217038 Year: Pages: 188 DOI: 10.3390/books978-3-03921-703-8 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Neurology
Added to DOAB on : 2019-12-09 11:49:16
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The prefrontal cortex (PFC) plays a pivotal role in regulating our emotions. The importance of ventromedial regions in emotion regulation, including the ventral sector of the medial PFC, the medial sector of the orbital cortex and subgenual cingulate cortex, have been recognized for a long time. However, it is increasingly apparent that lateral and dorsal regions of the PFC, as well as neighbouring dorsal anterior cingulate cortex, also play a role. Defining the underlying psychological mechanisms by which these functionally distinct regions modulate emotions and the nature and extent of their interactions is a critical step towards better stratification of the symptoms of mood and anxiety disorders. It is also important to extend our understanding of these prefrontal circuits in development. Specifically, it is important to determine whether they exhibit differential sensitivity to perturbations by known risk factors such as stress and inflammation at distinct developmental epochs. This Special Issue brings together the most recent research in humans and other animals that addresses these important issues, and in doing so, highlights the value of the translational approach.

Social Safety and Security

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ISBN: 9783039281466 / 9783039281473 Year: Pages: 112 DOI: 10.3390/books978-3-03928-147-3 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Law
Added to DOAB on : 2020-01-30 16:39:46
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Social safety in social environments entails the sense of feeling safe with other people. Thus, social safety and security are very important to our life. Although research in this area has made significant progress in the past few years, there are still many social problems that require attention and further development in order to secure peace of mind. There is a very clear and accurate understanding and judgment of the overall situation of social security in the current and future period. This Special Issue focuses on a number of contemporary issues in social safety and security. The objective of this book is to rapidly disseminate the latest research and knowledge in this important area.

Updates in Pediatric Sleep and Child Psychiatry

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ISBN: 9783038979388 / 9783038979395 Year: Pages: 160 DOI: 10.3390/books978-3-03897-939-5 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Pediatrics
Added to DOAB on : 2019-06-26 08:44:06
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Sleep-related symptoms are common in the majority of psychiatric diagnostic categories. The overlap of sleep and psychiatric disorders have been demonstrated in numerous studies. The understanding of sleep and child psychiatry has progressively evolved in the last decade and newer insights have developed regarding the complex interaction between sleep and psychopathology. This collection of articles represents updates on sleep and psychiatric disorders with medical and neurological co-morbidities in children and adolescents.

Diagnosis of Dementia and Cognitive Impairment

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ISBN: 9783039218844 / 9783039218851 Year: Pages: 140 DOI: 10.3390/books978-3-03921-885-1 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2020-01-07 09:08:26
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In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment. The methods of the assessments discussed extend from simple neurological signs, which may be elicited in the clinical encounter, through cognitive screening instruments, to sophisticated analyses of neuroimaging and cerebrospinal fluid biomarkers of disease. It is hoped that these various methods may facilitate earlier diagnosis of dementia and its subtypes, and provide differential diagnosis of depression and functional cognitive disorders, as a prelude to meaningful interventions.

Vitamin D and Human Health

ISBN: 9783038420569 9783038420576 Year: Pages: 476 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2015-10-22 08:50:54
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Vitamin D research has expanded greatly over the last 10 years, with a more than two-fold increase in annual publications listed in Pubmed with the key word ‘vitamin D’ from 1675 in 2005 to 3953 in 2014. Part of this increase is due to research showing that vitamin D deficiency is associated with a wide range of diseases and health outcomes. Until the 1980s, the primary focus of vitamin D research (in combination with calcium supplementation) was on bone diseases. Since then, observational studies have linked vitamin D deficiency with increased risk of many diseases: both acute and chronic. This book contains publications on several of these disease groups linked to vitamin D deficiency.

Internet and Mobile Phone Addiction. Health and Educational Effects

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ISBN: 9783038976042 Year: Pages: 328 DOI: 10.3390/books978-3-03897-605-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Psychology
Added to DOAB on : 2019-03-21 15:50:41
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Internet use-related addiction problems (e.g., Internet addiction, problem mobile phone use, problem gaming, and social networking) have been defined according to the same core element: the addictive symptomatology presented by individuals who excessively and problematically behave using the technology. Online activity is the most important factor in their lives, causing them the loss of control by stress and difficulties in managing at least one aspect of their daily life, affecting users’ wellbeing and health. In 2018, Gaming Disorder was included as a mental disease in the 11th Revision of the International Classification of Diseases by the World Health Organization. In 2013, the American Psychiatric Association requested additional research on Internet Gaming Disorder. The papers contained in this e-Book provide unique and original perspectives on the concept, development, and early detection of the prevention of these health problems. They are diverse in the nature of the problems they deal with, methodologies, populations, cultures, and contain insights and a clear indication of the impact of individual, social, and environmental factors on Internet use-related addiction problems. The e-Book illustrates recent progress in the evolution of research, with great emphasis on gaming and smartphone problems, signaling areas in which research would be useful, even cross-culturally.

Keywords

commuting --- well-being --- personality --- gender --- stress --- Internet addiction --- Internet gaming disorder --- game device usage pattern --- smartphone --- comorbidity --- Internet gaming disorder --- IGD --- emotional regulation --- cognitive reappraisal --- suppression --- depression --- hostility --- internet gaming disorder --- Dickman Impulsivity Inventory-Short Version (DII) --- Brief Self-Control Scale (BSCS) --- Symptom Checklist-90-Revised (SCL-90-R) --- Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) --- Diagnostic and Statistical Manual for Mental Disorders (DSM-5) --- gambling --- video-game addiction --- screen addiction --- immersion --- problematic Internet use --- comorbidity --- cognitive distortion --- problematic smartphone use --- smartphone addiction --- social media --- approaches to learning --- deep approach to learning --- surface approach to learning --- smartphone --- problematic mobile phone use --- convergent design --- focus group --- survey --- internet gaming disorder --- impulsivity --- depression --- interpersonal relationships --- serial mediation --- Internet addiction --- mobile phone addiction --- online social network --- university students --- technological addictions --- behavioral addictions --- CERI --- CERM --- mobile phone dependence --- mobile phone use --- impulsivity --- China --- Internet addiction --- Internet-use disorder --- Internet literacy --- expectancies --- personality --- cultural differences --- pathological video-game use --- Internet Gaming Disorder --- comorbid psychopathology --- review --- Internet Use Disorder --- prevalence --- epidemiology --- adolescence --- latent profile analysis --- anxiety --- depression --- Internet addiction --- smartphone addiction --- propensity score --- Internet addiction --- coping strategies --- personality traits --- young people --- mobile phone use --- smartphone use --- Problematic Mobile Phone Use --- Problematic Mobile Phone Use Questionnaire --- psychometric testing --- measurement invariance --- time --- gaming disorder --- interpersonal relations --- self-efficacy --- self-control --- expectations --- fear of missing out (FOMO) --- social media --- problematic social media use (PSMU) --- phubbing --- teenagers --- adolescents --- addiction --- internet addiction --- mobile phone (or smartphone) use --- young children --- early childhood education --- parenting --- emergent bilinguals --- intergenerational language transmission --- behavioural addictions --- generalised versus specific problem Internet uses --- Internet addiction --- gaming disorder --- social networking --- mixed methods research

Measures of Spirituality/Religiosity—Description of Concepts and Validation of Instruments

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ISBN: 9783038977582 9783038977599 Year: Pages: 148 DOI: 10.3390/books978-3-03897-759-9 Language: eng
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Religion
Added to DOAB on : 2019-04-25 16:37:17
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Why do we need more questionnaires to measure aspects of spirituality/religiosity when we already have so many well-tried instruments in use? One answer is that research in this field is growing and that new research questions continuously do arise. Several of these new questions cannot be easily answered with the instruments designed for previous questions. The field is expanding and, consequently, the research topics. Meanwhile several multidimensional instruments were developed which cover existential, prosocial, religious and non-religious forms of spirituality, hope, peace and trust&mdash;and several more. The &lsquo;disadvantage&rsquo; of these instruments is the fact that some are conceptually broad and often rather unspecific, but they might be suited quite well for culturally and spiritually diverse populations when the intention is to compare such diverse groups. This is the reason why more research on new instruments is needed as can be found in this Special Issue, and to stimulate a critical debate about their pros and cons.

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