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Clinical Recovery from CNS Damage

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ISBN: 9783318023084 9783318023091 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 102998
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:22:14
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After decades of focusing on how to alleviate and prevent recurrence of acute CNS injuries, the emphasis has finally shifted towards repairing such devastating events and rehabilitation. This development has been made possible by substantial progress in understanding the scientific underpinnings of recovery as well as by novel diagnostic tools, and most importantly, by emerging therapies awaiting clinical trials. In this publication, several international experts introduce novel areas of neurological reorganization and repair following CNS damage. Principles and methods to monitor and augment neuroplasticity are explored in depth and supplemented by a critical appraisal of neurological repair mechanisms and possibilities to curtail disability using computer or robotic interfaces. Rather than providing a textbook approach of CNS restoration, the editors selected topics where progress is most imminent in this labyrinthine domain of medicine.

Aging and Health

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ISBN: 9783318027297 9783318027303 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103014
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:22:14
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Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging.

Comorbidity of Mental and Physical Disorders

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ISBN: 9783318026030 9783318026047 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103012
Subject: Public Health
Added to DOAB on : 2019-11-26 11:22:14
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This publication presents evidence about the magnitude and severe consequences of comorbidity of mental and physical illnesses from a personal and societal perspective. Leading experts address the huge burden of co-morbidity to the affected individual as well as the public health aspects, the costs to society and interaction with factors stemming from the context of socioeconomic developments. The authors discuss the clinical challenge of managing cardiovascular illnesses, cancer, infectious diseases and other physical illness when they occur with a range of mental and behavioral disorders, including substance abuse, eating disorders and anxiety. Also covered are the organization of health services, the training of different categories of health personnel and the multidisciplinary engagement necessary to prevent and manage comorbidity effectively.

The Vitamin A Story

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ISBN: 9783318021882 9783318021899 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103006
Subject: Public Health
Added to DOAB on : 2019-11-26 11:24:34
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This book shows how vitamin A deficiency – before the vitamin was known to scientists – affected millions of people throughout history. It is a story of sailors and soldiers, penniless mothers, orphaned infants, and young children left susceptible to blindness and fatal infections. We also glimpse the fortunate ones who, with ample vitamin A-rich food, escaped this elusive stalker. Why were people going blind and dying? To unravel this puzzle, scientists around the world competed over the course of a century. Their persistent efforts led to the identification of vitamin A and its essential role in health. As a primary focus of today’s international public health efforts, vitamin A has saved hundreds of thousands of lives. But, we discover, they could save many more were it not for obstacles erected by political and ideological zealots who lack a historical perspective of the problem.

Tattooed Skin and Health

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ISBN: 9783318027761 9783318027778 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103009
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:24:34
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With about 10–20% of the adult population in Europe being tattooed, there is a strong demand for publications discussing the various issues related to tattooed skin and health. Until now, only a few scientific studies on tattooing have been published. This book discusses different aspects of the various medical risks associated with tattoos, such as allergic reactions from red tattoos, papulo-nodular reactions from black tattoos as well as technical and psycho-social complications, in addition to bacterial and viral infections. Further sections are dedicated to the composition of tattoo inks, and a case is made for the urgent introduction of national and international regulations. Distinguished authors, all specialists in their particular fields, have contributed to this publication which provides a comprehensive view of the health implications associated with tattooing.

The Psychosomatic Assessment

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ISBN: 9783805598538 9783805598545 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103011
Subject: Psychiatry
Added to DOAB on : 2019-11-26 11:24:34
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Patient reported outcomes have become more and more important in clinical practice and research. Evaluating subjective perceptions of patients has become mandatory for a full assessment of treatment responses. In this context, clinimetrics, the science of clinical measurements, provides unprecedented opportunities for psychosomatic assessment. This volume illustrates how this approach can be translated into everyday practice complementing and improving the medical interview. The most sensitive and reliable clinical methods are presented for evaluating specific psychosocial aspects of disease, i.e. childhood adversities, life events and chronic stress, lifestyle, sexual function, subclinical and affective disturbances, personality, illness behavior, well-being and family dynamics. Each chapter provides practical illustrations as to how crucial information can be obtained with specific methods individualized according to the patients’ needs.

The Mystery of Yawning in Physiology and Disease

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ISBN: 9783805594042 9783805594059 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 102999
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:24:34
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Yawning is a stereotyped phylogenetically ancient phenomenon that occurs in almost all vertebrates. As an emotional behavior and an expressive movement, yawning has many consequences; nevertheless, it has so far been poorly addressed in medical research and practice. Bringing together the latest research from many fields, this volume integrates current insights within embryology, ethology, neurophysiology, psychology, fMRI and pathology. The phylogenetic and ontogenetic aspects of yawning offer an interesting perspective on human development, and its occurrence in neurological diseases - an area explored by only a few investigators - may provide useful clinical information. This book will make valuable and fascinating reading to neurologists, sleep specialists, psychologists, ethologists and pharmacologists, as well as to anybody interested in uncovering the mystery of yawning.

Personalized Nutrition

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ISBN: 9783805594271 9783805594288 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103003
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:24:34
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Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the ‘3rd Congress of the International Society of Nutrigenetics/Nutrigenomics’ held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included.

Psychiatry of Parkinson's Disease

Authors: --- ---
ISBN: 9783805598002 9783805598019 Year: Language: English
Publisher: Karger Grant: Knowledge Unlatched - 103010
Subject: Medicine (General)
Added to DOAB on : 2019-11-26 11:24:34
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Psychiatric symptoms are common in the neurological and geriatric care of patients with Parkinson’s disease. This book assembles short reviews from experts in the field to chart the various psychiatric syndromes known in Parkinson’s disease, their presentation, etiology and management. Presented are special topics on epidemiology of psychiatric symptoms, affective disorders and apathy, early cognitive impairment through to dementia, visuoperceptual dysfunction, psychotic disorders, sleep disturbances, impulse disorders and sexual problems. Further, rarely discussed issues, such as the relationship between somatoform disorders and parkinsonism are reviewed. This publication is essential reading for old age psychiatrists, gerontologists and neurologists who work with patients suffering from Parkinson’s disease.

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