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Frontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889199549 Year: Pages: 107 DOI: 10.3389/978-2-88919-954-9 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Psychiatry
Added to DOAB on : 2016-01-19 14:05:46
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Abstract

Developmental neuroscience research is on the cusp of unprecedented advances in the understanding of how variations in brain structure and function within neural circuits confer risk for symptoms of childhood psychiatric disorders. Novel dimensional approaches to illness classification, the availability of non-invasive, diverse and increasingly sophisticated methods to measure brain structure and function in humans in vivo, and advances in genetics, animal model and multimodal research now place brain-based biomarkers within reach in the field of psychiatry. These advances hold great promise for moving neuroscience research into the clinical realm. One exciting new area of translational research in child and adolescent psychiatry, is in the use of a variety of neuroscience research tools to track brain response to clinical intervention. Examples of this include: using longitudinal neuroimaging techniques to track changes in white matter microstructure following a training intervention for children with poor reading skills, or using functional imaging to compare brain activity before and after children with bipolar disorder begin taking psychotropic medication treatment. Brain stimulation is another cutting-edge research area where brain response to therapeutic intervention can be closely tracked with electroencephalography or other brain imaging modalities. Research using neuroscience tools to track brain response to clinical interventions is beginning to yield novel insights into the etiopathogenesis of psychiatric illness, and is providing preliminary feedback around how therapeutic interventions work in the brain to bring about symptom improvement. Using these novel approaches, neuroscience research may soon move into the clinical realm to target early pathophysiology, and tailor treatments to both individuals and specific neurodevelopmental trajectories, in an effort to alter the course of development and mitigate risk for a lifetime of morbidity and ineffective treatments. Excitement and progress in these areas must be tempered with safety and ethical considerations for these vulnerable populations. This research topic focuses on efforts to use neuroscience research tools to identify brain-based biomarkers of therapeutic response in child and adolescent psychiatry.

Brain Development and the Attention Spectrum

Authors: --- --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889194827 Year: Pages: 96 DOI: 10.3389/978-2-88919-482-7 Language: English
Publisher: Frontiers Media SA
Subject: Neurology --- Science (General)
Added to DOAB on : 2015-11-16 15:44:59
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Early-onset and enduring developmental deficits in attention, especially if combined with increased hyperactivity, and impulsivity, may result in constant impairments in multiple domains of personal life. The full spectrum of symptoms is characterized by a persistent pattern of inattention and/or hyperactivity-impulsivity, which is maladaptive and inconsistent with a comparable level of developmental age known as Attention Deficit Hyperactivity Disorder (ADHD). ADHD is considered one of the most common neurobehavioral disorders and of childhood, and among the most prevalent chronic health conditions.Given the wide heterogeneity and complex manifestations of the disorder, there is an importance in a developmental perspective that views ADHD as a multi-factorial disorder with multiple, causal processes, and pathways. The symptoms of ADHD should be cast, not as static or fixed neurobehavioral deficits, but rather in terms of underlying developmental processes.Even experienced professional might minimize the prevalence of a disorder among certain groups of patients. Therefore, the existence of attention disorders might become ""transparent"" for both the patient and the professional. This might lead to a non-accurate diagnosis, harm the treatment aspects and has potential non beneficial prognostic aspects.The developmental approach can provide predictions as to how characteristics associated with attention develop over time and how multiple risk and protective factors transact to impact it's development, as well as the development of a broad range of associated co-morbid features.Among children with mental retardation, autistic spectrum disorders, children who were born premature, born with low birth weight, as well as among those who suffer from chronic disorders (such as epilepsy, diabetes, chronic kidney disease or asthma), as well as among otherwise healthy preschoolers - the assessment of attention performance might be very challenging. In this research topic, we explore the latest cutting edge research on the biological and neural pathways as well as on psychosocial and behavioral correlates of brain development and attention spectrum. In doing so we aim to highlight: what is currently known regarding this new conceptualization of attention as a spectrum; the mechanisms underlying this spectrum; and where this field is headed in terms of developing our understanding of the link between brain development and attention performance.

Keywords

ADHD --- Attention --- Brain --- autism --- Child --- Delay --- development --- fetal --- maturation --- spectrum --- visual

The Role of Play in Child Assessment and Intervention

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889452590 Year: Pages: 150 DOI: 10.3389/978-2-88945-259-0 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Psychology
Added to DOAB on : 2018-02-27 16:16:44
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Play is a ubiquitous and universal aspect of early childhood. Although it may take different forms throughout development and across cultures, decades of research have found play to be related to important, positive outcomes. Play provides children with valuable cognitive, emotional, and interpersonal learning opportunities. It can act as a mode of communication for young children and allows them to practice ways of managing complex interpersonal interactions. Specific aspects of play, such as children’s creativity in pretend play, have been associated with resilience and coping. The significance of play in childhood has led to its frequent use in the assessment of child development and in the implementation of child and parent-child psychological and educational interventions. Historically, however, the validity and efficacy of these interventions have not been rigorously evaluated. Further, few assessment and intervention models have included parents, teachers, and other key caregivers, but have focused only on the child. This Research Topic will bring together the most current literature on the use of play in child assessment and intervention.

Neuromuscular Training and Adaptations in Youth Athletes

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889456277 Year: Pages: 308 DOI: 10.3389/978-2-88945-627-7 Language: English
Publisher: Frontiers Media SA
Subject: Science (General) --- Physiology
Added to DOAB on : 2019-01-23 14:53:43
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The Frontiers Research Topic entitled "Neuromuscular Training and Adaptations in Youth Athletes" contains one editorial and 22 articles in the form of original work, narrative and systematic reviews and meta-analyses.From a performance and health-related standpoint, neuromuscular training stimulates young athletes' physical development and it builds a strong foundation for later success as an elite athlete. The 22 articles provide current scientific knowledge on the effectiveness of neuromuscular training in young athletes.

Motor Skills and Their Foundational Role for Perceptual, Social, and Cognitive Development

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889451593 Year: Pages: 293 DOI: 10.3389/978-2-88945-159-3 Language: English
Publisher: Frontiers Media SA
Subject: Psychology --- Science (General)
Added to DOAB on : 2017-08-28 14:01:09
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Motor skills are a vital part of healthy development and are featured prominently both in physical examinations and in parents’ baby diaries. It has been known for a long time that motor development is critical for children’s understanding of the physical and social world. Learning occurs through dynamic interactions and exchanges with the physical and the social world, and consequently movements of eyes and head, arms and legs, and the entire body are a critical during learning. At birth, we start with relatively poorly developed motor skills but soon gain eye and head control, learn to reach, grasp, sit, and eventually to crawl and walk on our own. The opportunities arising from each of these motor milestones are profound and open new and exciting possibilities for exploration and interactions, and learning. Consequently, several theoretical accounts of child development suggest that growth in cognitive, social, and perceptual domains are influences by infants’ own motor experiences. Recently, empirical studies have started to unravel the direct impact that motor skills may have other domains of development. This volume is part of this renewed interest and includes reviews of previous findings and recent empirical evidence for associations between the motor domain and other domains from leading researchers in the field of child development. We hope that these articles will stimulate further research on this interesting question.

Disclosure Within HIV-Affected Families

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889455263 Year: Pages: 130 DOI: 10.3389/978-2-88945-526-3 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General) --- Public Health
Added to DOAB on : 2019-01-23 14:53:42
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While HIV/AIDS is a global public heath challenge, its impact is arguably greatest in the Sub-Saharan Africa (SSA), where new infections account for approximately 66% of the total number of HIV-positive persons globally. In SSA, medical, social, and economic resources are limited, thus necessitating innovative approaches to disease prevention. One of the mechanisms of prevention that is most promising occurs through HIV disclosure to family members (e.g., adult sexual partners) generally, and to children in particular. Our emphasis in this eBook is on HIV disclosure to children because it has multiple benefits, including improved adherence to antiretroviral medication treatment and understanding at an early age of the impact of sexual activity on the spread of HIV. While there is a noticeable gap in research on HIV disclosure to younger children, some of the general reasons for non-disclosure include concerns about fear of adult partners leaving relationships, and that children are too young to comprehend the severity of the situation and may tell others outside the family. Thus, it is critical to better understand how the HIV disclosure process happens (or does not happen) within HIV-affected families, as well as the best practices on how to disclose. In this eBook, we present a combination of empirical research studies and critical literature reviews that investigate the reasons for and for not disclosing HIV status within HIV-affected families and provide evidence-based practices that could be adopted by healthcare professionals to help HIV-positive parents facilitate disclosure activities within these families. This information can also be used by researchers, practitioners, and stakeholders who are in a position to influence policies on effective HIV disclosure practices, guidelines, and programs.

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