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Genome Informatics 2009:Genome Informatics Series Vol. 22

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Book Series: Genome Informatics Series ISBN: 9781848165786 Year: Pages: 228 DOI: 10.1142/p718 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 04:29:21

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This volume contains 17 peer-reviewed papers based on the presentations at the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) held at the Life Science Engineering Building of Boston University from July 27 to 29, 2009. This workshop started in 2001 as a platform for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following institutions and programs:Boston University Graduate Program in BioinformaticsCharité – Universitätsmedizin BerlinFreie Universität BerlinGlobal COE Program — Center of Education and Research for Advanced Genome-Based Medicine, University of TokyoThe International Research Training Group (IRTG) Genomics and Systems Biology of Molecular NetworksInternational Research and Training Program on Bioinformatics and Systems Biology, Kyoto University Bioinformatics CenterMax-Delbrück Center for Molecular Medicine in BerlinMax Planck Institute for Molecular Genetics in BerlinMax Planck Institute of Molecular Plant Physiology in Potsdam

Genome Informatics 2009:Genome Informatics Series Vol. 23

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Book Series: Genome Informatics Series ISBN: 9781848165632 Year: Pages: 240 DOI: 10.1142/p715 Language: ENGLISH
Publisher: World Scientific Publishing Co.
Added to DOAB on : 2019-07-04 04:35:35

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This volume contains papers presented at the 20th International Conference on Genome Informatics (GIW 2009) held at the Pacifico Yokohama, Japan from December 14 to 16, 2009. The GIW Series provides an international forum for the presentation and discussion of original research papers on all aspects of bioinformatics, computational biology and systems biology. Its scope includes biological sequence analysis, protein structure prediction, genetic regulatory networks, bioinformatic algorithms, comparative genomics, and biomolecular data integration and analysis. Boasting a history of 20 years, GIW is the longest-running international bioinformatics conference.A total of 18 contributed papers were selected for presentation at GIW 2009 and for inclusion in this book. In addition, this book contains abstracts from the five invited speakers: Sean Eddy (HHMI's Janelia Farm, USA), Minoru Kanehisa (Kyoto University, Japan), Sang Yup Lee (KAIST, Korea), Hideyuki Okano (Keio University, Japan) and Mark Ragan (University of Queensland, Australia).

Tumor Metastasis

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ISBN: 9789535126300 9789535126317 9789535141815 Year: Pages: 266 DOI: 10.5772/61798 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:49

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Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis.

Free Radicals and Diseases

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ISBN: 9789535127468 9789535127475 9789535141655 Year: Pages: 386 DOI: 10.5772/61358 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:49

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The current volume entitled, ""Free Radicals and Diseases"" integrates knowledge in free radical-associated diseases from the basic level to the advanced level, and from the bench side to bed side. The chapters in this book provide an extensive overview of the topic, including free radical formations and clinical interventions.

A Master Regulator of Oxidative Stress - The Transcription Factor Nrf2

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ISBN: 9789535128373 9789535128380 Year: Pages: 210 DOI: 10.5772/62743 Language: English
Publisher: IntechOpen
Subject: Biology
Added to DOAB on : 2019-10-03 07:51:49

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Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

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ISBN: 9789535133353 9789535133360 Year: Pages: 192 DOI: 10.5772/65504 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:50

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The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.

Stem Cells in Clinical Practice and Tissue Engineering

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ISBN: 9781789230109 9781789230116 Year: Pages: 352 DOI: 10.5772/65995 Language: English
Publisher: IntechOpen
Subject: Cytology
Added to DOAB on : 2019-10-03 07:51:51

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Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Cancer Management and Therapy

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ISBN: 9781789232981 9781789232998 Year: Pages: 210 DOI: 10.5772/intechopen.68267 Language: English
Publisher: IntechOpen
Subject: Oncology
Added to DOAB on : 2019-10-03 07:51:51

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There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters.

Molecular Docking

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ISBN: 9781789233544 9781789233551 Year: Pages: 188 DOI: 10.5772/intechopen.69830 Language: English
Publisher: IntechOpen
Subject: Biology
Added to DOAB on : 2019-10-03 07:51:51

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Molecular docking has always been and will be on the forefront of developments in the eminent field of drug design and medicinal chemistry. At the early days, drug discovery was based on blackboard drawings and expert intuition. However, as times move on, the amount of available information and overall knowledge base that needs to be analyzed cannot be processed manually. This, coupled by the rapid growth in computational infrastructure and processing power, has allowed for the efficient use of molecular docking tools and algorithms to be considered in the greater field of drug discovery. In the postgenomic era, molecular docking has become the key player for the screening of hundreds of thousands of compounds against a repertoire of pharmacological targets.

Free Radicals, Antioxidants and Diseases

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ISBN: 9781789235647 9781789235654 Year: Pages: 148 DOI: 10.5772/intechopen.70075 Language: English
Publisher: IntechOpen
Subject: Biology
Added to DOAB on : 2019-10-03 07:51:51

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The current book entitled Free Radicals, Antioxidants, and Diseases gives an idea of detecting free radicals in vivo by newer techniques and provides insights into the roles played by various antioxidants in combating diseases caused by oxidative stress. The chapters included in this volume showcase new investigation in this field by the research groups around the world.

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