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Chapter 5 Mercury Tonics (Rasāyana) in Sanskrit Medical Literature (Book chapter)

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ISBN: 9781781791288 9781781791288 9781781791295 9781781794364 9781781794371 Year: Pages: 21 Language: English
Publisher: Equinox Grant: H2020 European Research Council - 639363
Subject: Medicine (General) --- History
Added to DOAB on : 2019-01-15 13:34:35
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This chapter will provide a brief survey of the uses of mercury preparations in rasāyana therapy, discussing their position within rejuvenation therapy in regard to other rasāyana formulations and exploring their link with Indian alchemical traditions.

Keywords

History --- Indian medicine --- therapy

Advances in the Prevention and Management of Obesity and Eating Disorders

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ISBN: 9783038428534 9783038428541 Year: Pages: VIII, 192 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General)
Added to DOAB on : 2018-05-18 12:02:38
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Obesity and eating disorders remain major public health concerns worldwide that often co-exist. While we are far from having definitive solutions, scientific insights into the prevention and management of obesity and eating disorders have developed significantly in recent years. This research has been stimulated by the continuous challenge of reducing the global burden of obesity and its commonly associated health complications, as well as the life-threatening characteristics of eating disorders. Looking towards better solutions for these pressing public health concerns, this book addresses recent scientific findings regarding the prevention and management of obesity and eating disorders. It reports on cognition and mental health in people with obesity, as well as on food addiction, co-morbidities of eating disorders, cultural aspects of eating, intermittent dietary energy restriction as a treatment for overweight or obesity, factors influencing the adherence to dietary treatments for overweight and obesity, philosophies underpinning dietary practices, treatment of eating disorders in men, cognitive remediation therapy for anorexia nervosa, and online or virtual interventions for weight management or bulimia nervosa. This book includes culturally diverse findings from research groups around the world (e.g. Australia, UK, Norway, Brazil), and is informative for healthcare professionals and researchers working in the fields of obesity and/or eating disorders.

Novel Molecular Approaches to Target Microbial Virulence

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ISBN: 9783110449501 9783110449617 Year: Pages: 87 DOI: 10.1515/9783110449501 Language: English
Publisher: De Gruyter
Subject: Biotechnology --- Microbiology --- Internal medicine
Added to DOAB on : 2016-01-06 13:06:10
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Microbial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alternative methods to handle infections and reduce resistance and other side effects produced by the actual therapies. The aim of this book is to offer a perspective on novel approaches to handle infections by using naturally-derived products in order to modulate the virulence of pathogens, without the risk of developing resistance. We intend to highlight the utility of microbial, vegetal and animal–derived compounds with potential antimicrobial activity by exploiting their effect on microbial virulence. Furthermore, this book aims to reveal the potential to assimilate recent bio-technological findings, like the usage of nanotechnology as efficient shuttles for stabilizing, improved targeting and the controlled release of natural products in order to efficiently fight infections.

Soaking up the rays: Light therapy and visual culture in Britain, c. 1890–1940

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ISBN: 9781526115980 Year: Pages: 288 Language: English
Publisher: Manchester University Press Grant: Wellcome Trust - 098912
Subject: Medicine (General) --- History --- History of arts
Added to DOAB on : 2017-08-10 11:01:42
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Soaking up the rays forges a new path for exploring Britain’s fickle love of the light by investigating the beginnings of light therapy in the country, from c.1890–1940. Despite rapidly becoming a leading treatment for tuberculosis, rickets and other infections and skin diseases, light therapy was a contentious medical practice. Bodily exposure to light, whether for therapeutic or aesthetic ends, persists as a contested subject to this day: recommended to counter psoriasis and other skin conditions as well as Seasonal Affective Disorder (SAD) and depression; closely linked to notions of beauty, happiness and well-being, fuelling tourism to sunny locales abroad and the tanning industry at home; and yet with repeated health warnings that it is a dangerous carcinogen. By analysing archival photographs, illustrated medical texts, advertisements, lamps, and goggles and their visual representation of how light acted upon the body, Woloshyn assesses their complicated contribution to the founding of light therapy. Soaking up the rays will appeal to those intrigued by medicine’s visual culture, especially academics and students of the histories of art and visual culture, material cultures, medicine, science and technology, and popular culture.

Natural Products for Cancer Prevention and Therapy

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ISBN: 9783038973102 9783038973119 Year: Pages: 260 DOI: 10.3390/books978-3-03897-311-9 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Medicine (General) --- Oncology --- Therapeutics
Added to DOAB on : 2018-11-07 10:17:54
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ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[This Special Issue book, “Natural Products for Cancer Prevention and Therapy”, is based on recent advances in natural products for cancer prevention and therapy. For this purpose, the authors of this book have been organizing a biennial international conference series. The first meeting (First International Conference on Natural Products for Cancer Prevention and Therapy) was held in Istanbul between 31 August and 2 September 2015, with the support and contribution of many valuable researchers in this field. The abstracts of the first conference were published in the Anticancer Drugs journal as a supplement. The second meeting, namely The Second International Conference on Natural Products for Cancer Prevention and Therapy, was held at Erciyes University, Kayseri, Turkey, between 8 and 11 November 2017. The abstracts of all of the presentations from the second meeting were published in the Special Issue of Proceedings by the MDPI publishing group. Furthermore, the conference report and the selected full-length papers based on the presentations at the meeting, as well as other papers based on natural products for cancer prevention and therapy, were published as a Special Issue of the Nutrients journal from MDPI. This Special Issue has contributions from various participants of the aforementioned conference, as well as other cancer and natural product researchers. These contributions include original research papers, authoritative and up-to-date reviews, and commentaries on the following topics and areas:•Natural products for the prevention and therapy of oncologic diseases•Mechanism of natural agents for anticancer and cancer preventive effects•In vitro, in vivo, and clinical studies related to natural agents and cancer•Combinatorial effects of phytochemicals and cancer chemotherapeutic drugs•Challenges and innovative approaches for anticancer drug development based on natural products•Emerging studies on anticancer phytochemicals]

Computer assisted optimization of cardiac resynchronization therapy

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Book Series: Karlsruhe transactions on biomedical engineering / Ed.: Universität Karlsruhe (TH) / Institute of Biomedical Engineering ISSN: 18645933 ISBN: 9783866443600 Year: Volume: 6 Pages: IV, 293 p. DOI: 10.5445/KSP/1000011293 Language: ENGLISH
Publisher: KIT Scientific Publishing
Subject: Technology (General)
Added to DOAB on : 2019-07-30 20:02:02
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The efficacy of cardiac resynchronization therapy (CRT) through biventricular pacing (BVP) has been demonstrated by numerous studies in patients suffering from congestive heart failure. In order to achieve a guideline for optimal treatment with BVP devices, an automated non-invasive strategy based on an electrophysiological computer model of the heart is presented. The presented research investigates an off-line optimization algorithm based on different electrode positioning and timing delays.

Hurdles for Phage Therapy (PT) to Become a Reality

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ISBN: 9783039213917 9783039213924 Year: Pages: 484 DOI: 10.3390/books978-3-03921-392-4 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Science (General) --- Biology --- Microbiology
Added to DOAB on : 2019-12-09 11:49:15
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Alternative treatment modes for antibiotic-resistant bacterial pathogens have become a public health priority. Bacteriophages are bacterial viruses that infect and lyse bacterial cells. Since bacteriophages are frequently bacterial host species-specific and can often also infect antibiotic-resistant bacterial cells, they could represent ideal antimicrobials for fighting the antibiotic resistance crisis. The medical use of bacteriophages has become known as phage therapy. It is widely used in Russia, where phage cocktails are sold in pharmacies as an over-the-counter drug. However, no phage product has been registered for medical purposes outside of the former Soviet Union. The current Special Issue of Viruses contains a collection of papers from opinion leaders in the field who explore hurdles to the introduction of phage therapy in western countries. The articles cover diverse topics ranging from patent to regulatory issues, the targeting of suitable bacterial infections, and the selection and characterization of safe and efficient phage cocktails. Phage resistance is discussed, and gaps in our knowledge of phage–bacterium interactions in the mammalian body are revealed, while other articles explore the use of phages in food production and processing.

Keywords

Staphylococcus aureus --- bacteriophage --- phage therapy --- vB_SauM-fRuSau02 --- Twortlikevirus --- antibiotic --- antimicrobial resistance --- magistral preparation --- compounding pharmacy --- phage therapy --- regulatory framework --- personalized medicine --- bacteriophage --- phage --- horizontal gene transfer --- co-evolution --- phage therapy --- industrial phage application --- antimicrobial resistance (AMR) --- Germany --- pH stability --- phage-host interactions --- genomics --- antibiotic-resistance --- phage preparation --- lysins --- biofilms --- typhoid fever --- Salmonella Typhi --- extended-spectrum beta lactamases (ESBL) --- Democratic Republic of the Congo --- bacteriophages --- MALDI-MS --- Staphylococcus --- bacteriophages --- phage therapy --- Kayvirus --- Viral proteins --- bacteriophage --- therapy --- phage therapy --- bacterial disease --- infection --- target selection --- Bacteriophage --- phage therapy --- resistance --- adaptation --- prophage --- production --- regulation --- phage therapy --- viral genomes --- best practices --- IND --- high-throughput sequencing --- bacteriophages --- phages --- food safety --- foodborne illness --- phage therapy --- history of science --- science communication --- bacteriophage --- phage therapy --- sustainable agriculture --- zoonosis --- antibiotic resistance --- phage therapy --- experimental therapy --- phage cocktails --- anti-phage antibodies --- prophage --- immunomodulation --- phage therapy --- evolution --- bacterial resistance --- virulence --- Listeria ivanovii --- bacteriophages --- alginate --- production --- disinfection --- phagodisinfection --- virus–host interactions --- bacteriophage efficacy --- gastrointestinal tract --- phage therapy --- bacteriophage --- phage therapy --- antimicrobial resistance --- antibiotic --- global health --- developing countries --- infectious disease --- bacteriophage --- phage --- phage therapy --- phage-resistance --- phage therapy --- bacterial infection --- capsule depolymerase --- antibiotic --- animal model --- bacterial resistance --- bacteriophage --- immunology --- innate immunity --- adaptive immunity --- human host --- phage-human host interaction --- bacterial infection --- antibiotic resistance --- bacteriophage --- antibiotic therapy --- phage therapy --- cases report --- abortive infection --- prophage --- adsorption --- Enterococcus --- rhamnopolysaccharide --- bacteriophage --- phage therapy --- Staphylococcus aureus --- biofilm --- antimicrobial --- frequency of resistance --- phage sensitivity --- resistance management --- nontraditional antibacterial --- bacteriophages --- phage therapy --- antibiotic resistance --- Pseudomonas aeruginosa --- Escherichia coli --- Staphylococcus aureus --- Brussels --- Belgium --- phage biocontrol --- patent landscape --- crop production --- bacteriophage --- phage therapy --- multidrug-resistant bacteria --- antimicrobial resistance --- bacteriophage therapy --- compassionate use --- antibiotic resistance --- phage therapy --- PTMP --- ATMP --- regulatory framework --- pharmaceutical paradigm shift --- clinical trial --- magistral formula --- personalized medicine --- phage therapy --- E. faecalis --- OrthoMCL --- antimicrobial resistance --- capsule --- Galleria mellonella --- Klebsiella pneumoniae --- phage therapy --- n/a --- antimicrobial resistance --- bacteriophage --- personalised medicines --- phage therapy --- pharmaceutical legislation --- regulatory framework

The Biology and Treatment of Myeloid Leukaemias

Authors: ---
ISBN: 9783038427957 9783038427964 Year: Pages: VI, 190 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Oncology
Added to DOAB on : 2018-04-17 13:45:41
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There has been an observed decrease in the global mortality from cancer, mostly atributable to improved, particularly early, detection and prevention. For many carcinomas and leukaemias in adults, once the disease has reached a certain stage there are no therapies that are able to erradicate the cancer cells and cure patients. There has been progress in the treatment of acute myeloid leukaemia (AML) and remissions are achievable; however, the presence of chemoresistent blast cells leads to most patients relapsing, and relapse is difficult to treat and thus patients die due to their disease. Targeting these resistent cells and the leukaemia stem cells, which sustain the leukaemia, is crucial for an effective therapy for AML. Moreover, an increasing number of diverse mutations have been described in AML cells that disrupt the ability of these cells to undergo differentiation. The use of pro-differentiating agents to drive the blast cells to mature, and subsequently undergo apoptosis, provides another approach to therapy. Differentiation therapy, using all-trans retinoic acid (ATRA), an inducer of granulocyte differentiation, has been highly successful in the case of acute promyeloicytic leukaemia, a sub-type of AML, turning this disease into a curable malignancy.

Perspektiven des Medizinrechts im 21. Jahrhundert

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ISBN: 9783940344083 Year: DOI: 10.17875/gup2007-31 Language: German
Publisher: Universitätsverlag Göttingen
Subject: Law
Added to DOAB on : 2011-11-04 00:00:00
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Series "Göttinger Schriften zum Medizinrecht" (medicine law), which deals with several important debates in modern medicine such as gene therapy, research with embryonic stem cells, bio databases, living organ donation, and in general the economisation of the health system.

Mass Spectrometry Application in Biology

ISBN: 9783906980898 9783906980904 Year: Pages: 252 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2015-10-22 06:39:08
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Mass spectrometry (MS) has become a vital tool for scientist in exploring how biological systems function and how therapeutic drug intervention (both small molecules and biologics) impact these systems. The application of mass spectrometry has advanced our knowledge in the biological sciences through the study of proteins and peptides in proteomics and as biomarkers, imaging via MALDI MS, and analysis of SNP’s in the genome to allow personalized medical treatment.The aim of this book is to provide a glimpse of some of the many applications of the advancing field of mass spectrometry and its application to complex biological problems. The topics presented here touch on many of the areas listed above will hopefully serve as a catalyst to generate new ideas for the continued innovative application of mass spectrometry to the fields of medicine, biology and beyond.

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