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On the Origin and Function of Human NK-like CD8+ T Cells: Charting New Territories

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889453962 Year: Pages: 121 DOI: 10.3389/978-2-88945-396-2 Language: English
Publisher: Frontiers Media SA
Subject: Allergy and Immunology --- Medicine (General)
Added to DOAB on : 2018-11-16 17:17:57
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Human CD8+ T cells expressing NK receptors and receptors found on innate immune cells, and designated as NK-like or innate CD8+ T cells, have been long considered as terminally differentiated lymphocytes responsible for tissue inflammation and destruction. However, a growing body of knowledge is unveiling that NK-like CD8+ T cells have many, sometimes contrasting, functions. The limited knowledge of the biology of this type of CD8+ T cells and the role they play within peripheral tissues and organs under homeostatic conditions has hampered our understanding of disease and therefore the possible development of disease diagnostic tools and effective immunotherapies. In this Research Topic are presented a variety of topics and views, some of them overlooked for many years, on human NK-like CD8+ T cells, which may open new and novel avenues of research to further our understanding of these polyfunctional T cells.

Asian Century… on a Knife-edge: A 360 Degree Analysis of Asia's Recent Economic Development

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ISBN: 9789811071812 9789811071829 Year: Pages: 335 DOI: 10.1007/978-981-10-7182-9 Language: English
Publisher: Palgrave Macmillan Grant: Asian Century Institute
Subject: Economics --- Political Science
Added to DOAB on : 2018-05-31 18:10:53
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This book delves into the widely held belief that the 21st century will be the "Asian Century" by examining the Asia's rapid economic development in the post-war era and the challenges it faces in forging ahead of world leaders in the West.The impact of the current turbulent global political climate on Asia is critically analyzed, employing a holistic and multidisciplinary approach, combining economic, social, political and geopolitical perspectives. Written in an accessible style, the book offers students, business, government, and civil society players powerful insights on Asia.

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