Search results: Found 7

Listing 1 - 7 of 7
Sort by
Mechanics of Biomaterials

ISBN: 9783038421283 9783038421276 Year: Pages: 286 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2016-05-10 11:55:10
License:

Loading...
Export citation

Choose an application

Abstract

The mechanical behavior of biomedical materials and biological tissues are important for their proper function. This holds true, not only for biomaterials and tissues whose main function is structural such as skeletal tissues and their synthetic substitutes, but also for other tissues and biomaterials. Moreover, there is an intimate relationship between mechanics and biology at different spatial and temporal scales. It is therefore important to study the mechanical behavior of both synthetic and livingbiomaterials. This Special Issue aims to serve as a forum for communicating the latest findings and trends in the study of the mechanical behavior of biomedical materials.

Non-thermal Plasma Technology for the Improvement of Scaffolds for Tissue Engineering and Regenerative Medicine - A Review (Book chapter)

Book title: Plasma Science and Technology - Progress in Physical States and Chemical Reactions

Authors: --- --- --- --- et al.
ISBN: 9789535122807 Year: DOI: 10.5772/62007 Language: English
Publisher: IntechOpen Grant: FP7 Ideas: European Research Council - 279022
Subject: Science (General)
Added to DOAB on : 2019-01-17 11:48:00
License:

Loading...
Export citation

Choose an application

Abstract

Non-thermal plasma technology is one of those techniques that suffer relatively little from diffusion limits, slow kinetics, and complex geometries compared to more traditional liquid-based chemical surface modification techniques. Combined with a lack of solvents, preservation of the bulk properties, and fast treatment times; it is a well-liked technique for the treatment of materials for biomedical applications. In this book chapter, a review will be given on what the scientific community determined to be essential to obtain appropriate scaffolds for tissue engineering and how plasma scientists have used non-thermal plasma technology to accomplish this. A distinction will be made depending on the scaffold fabrication technique, as each technique has its own set of specific problems that need to be tackled. Fabrication techniques will include traditional fabrication methods, rapid prototyping, and electrospinning. As for the different plasma techniques, both plasma activation and grafting/polymerization will be included in the review and linked to the in-vitro/in-vivo response to these treatments. The literature review itself is preceded by a more general overview on cell communication, giving useful insights on how surface modification strategies should be developed.

Biomineralization

Authors: --- ---
ISBN: 9789811310027 Year: Pages: 413 DOI: 10.1007/978-981-13-1002-7 Language: English
Publisher: Springer
Subject: Agriculture (General) --- Biology --- Mathematics --- Medicine (General)
Added to DOAB on : 2020-02-04 11:21:26
License:

Loading...
Export citation

Choose an application

Abstract

This open access book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research.

Biomaterials and Bioactive Molecules to Drive Differentiation in Striated Muscle Tissue Engineering

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889198412 Year: Pages: 90 DOI: 10.3389/978-2-88919-841-2 Language: English
Publisher: Frontiers Media SA
Subject: Physiology --- Science (General)
Added to DOAB on : 2016-01-19 14:05:46
License:

Loading...
Export citation

Choose an application

Abstract

Tissue engineering is an innovative, multidisciplinary approach which combines (bio)materials, cells and growth factors with the aim to obtain neo-organogenesis to repair or replenish damaged tissues and organs. The generation of engineered tissues and organs (e. g. skin and bladder) has entered into the clinical practice in response to the chronic lack of organ donors. In particular, for the skeletal and cardiac muscles the translational potential of tissue engineering approaches has clearly been shown, even though the construction of this tissue lags behind others given the hierarchical, highly organized architecture of striated muscles. Cardiovascular disease is the leading cause of death in the developed world, where the yearly incidence of Acute MI (AMI) is approx 2 million cases in Europe. Recovery from AMI and reperfusion is still less than ideal. Stem cell therapy may represent a valid treatment. However, delivery of stem cells alone to infarcted myocardium provides no structural support while the myocardium heals, and the injected stem cells do not properly integrate into the myocardium because they are not subjected to the mechanical forces that are known to drive myocardial cellular physiology. On the other hand, there are many clinical cases where the loss of skeletal muscle due to a traumatic injury, an aggressive tumour or prolonged denervation may be cured by the regeneration of this tissue. In vivo, stem or progenitor cells are sheltered in a specialized microenvironment (niche), which regulates their survival, proliferation and differentiation. The goal of this research topic is to highlight the available knowledge on biomaterials and bioactive molecules or a combination of them, which can be used successfully to differentiate stem or progenitor cells into beating cardiomyocytes or organized skeletal muscle in vivo. Innovations compared to the on-going trials may be: 1) the successful delivery of stem cells using sutural scaffolds instead of intracoronary or intramuscular injections; 2) protocols to use a limited number of autologous or allogeneic stem cells; 3) methods to drive their differentiation by modifying the chemical-physical properties of scaffolds or biomaterials, incorporating small molecules (i.e. miRNA) or growth factors; 4) methods to tailor the scaffolds to the elastic properties of the muscle; 5) studies which suggest how to realize scaffolds that optimize tissue functional integration, through the combination of the most up-to-date manufacturing technologies and use of bio-polymers with customized degradation properties.

Putting the "why" back into bone "archytecture"

Authors: --- ---
Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889193110 Year: Pages: 82 DOI: 10.3389/978-2-88919-311-0 Language: English
Publisher: Frontiers Media SA
Subject: Internal medicine --- Medicine (General)
Added to DOAB on : 2017-02-03 17:04:57
License:

Loading...
Export citation

Choose an application

Abstract

A large literature exists on trabecular and cortical bone morphology. The engineering performance of bone, implied from its 3d architecture, is often the endpoint of bone biology experiments, being clinically relevant to bone fracture. How and why does bone travel along its complex spatio-temporal trajectory to acquire its architecture? The question "why" can have two meanings. The first, "teleological - why is an architecture advantageous?" – is the domain of substantial biomechanical research to date. The second, "etiological – how did an architecture come about?" – has received far less attention. This Frontiers Bone Research Topic invited contributions addressing this "etiological why" – what mechanisms can coordinate the activity of bone forming and resorbing cells to produce the observed complex and efficient bone architectures? One mechanism is proposed – chaotic nonlinear pattern formation (NPF) which underlies – in a unifying way – natural structures as disparate as trabecular bone, swarms of birds flying or shoaling fish, island formation, fluid turbulence and others. At the heart of NPF is the fact that simple rules operating between interacting elements multiplied and repeated many times, lead to complex and structured patterns. This paradigm of growth and form leads to a profound link between bone regulation and its architecture: in bone "the architecture is the regulation". The former is the emergent consequence of the latter. Whatever mechanism does determine bone's developing architecture has to operate at the level of individual sites of formation and resorption and coupling between the two. This has implications as to how we understand the effect on bone of agents such as gene products or drugs. It may be for instance that the "tuning" of coupling between formation and resorption might be as important as the achievement of enhanced bone volume. The ten articles that were contributed to this Topic were just what we hoped for – a snapshot of leading edge bone biology research which addresses the question of how bone gets its shape. We hope that you find these papers thought-provoking, and that they might stimulate new ideas in the research into bone architecture, growth and adaptation, and how to preserve healthy bone from gestation and childhood until old age.

Bio-based Building Skin

Authors: --- --- ---
Book Series: Environmental Footprints and Eco-design of Products and Processes ISBN: 9789811337475 Year: Pages: 183 DOI: 10.1007/978-981-13-3747-5 Language: English
Publisher: Springer
Subject: Agriculture (General) --- Science (General) --- Architecture
Added to DOAB on : 2020-01-29 11:21:04
License:

Loading...
Export citation

Choose an application

Abstract

This book provides a compendium of material properties, demonstrates several successful examples of bio-based materials’ application in building facades, and offers ideas for new designs and novel solutions. It features a state-of-the-art review, addresses the latest trends in material selection, assembling systems, and innovative functions of facades in detail. Selected case studies on buildings from diverse locations are subsequently presented to demonstrate the successful implementation of various biomaterial solutions, which defines unique architectural styles and building functions. The structures, morphologies and aesthetic impressions related to bio-based building facades are discussed from the perspective of art and innovation; essential factors influencing the performance of materials with respect to functionality and safety are also presented. Special emphasis is placed on assessing the performance of a given facade throughout the service life of a building, and after its end. The book not only provides an excellent source of technical and scientific information, but also contributes to public awareness by demonstrating the benefits to be gained from the proper use of bio-based materials in facades. As such, it will appeal to a broad audience including architects, engineers, designers and building contractors. ; Presents case-studies and latest trends in material selection, assembling systems, and innovative functions of facades Discusses structure morphologies and aesthetic impressions related to bio-based building facades Highlights factors influencing performance of facades, with a special focus on service life of the building

Organic Semiconductors

ISBN: 9783906980966 9783906980973 Year: Pages: 260 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Added to DOAB on : 2015-10-22 07:55:44
License:

Loading...
Export citation

Choose an application

Abstract

Over the last few years Organic Semiconducting industry showed significant growth in many areas dominated by conventional electronics. The foremost advantage of organic materials is that they are cheap, lightweight and flexible. In addition, the fabrication of organic materials from a defined molecular precursor using inkjet−printing technology is simple, bypassing the need for advanced semiconductor processing techniques. Organic thin films have already found confirmed and reliable applications in flexible displays, solar cells and biomedical applications, including implantable devices. Low cost materials, compatible with current organic electronic fabrication techniques and which improve device performance are in strong demand.This special issue of Organic Semiconductors covers Materials, Fabrication Techniques, Characterization, Devices and market adoption of Organic Semiconductors.

Listing 1 - 7 of 7
Sort by
Narrow your search

Publisher

Frontiers Media SA (2)

MDPI - Multidisciplinary Digital Publishing Institute (2)

Springer (2)

IntechOpen (1)


License

CC by (7)


Language

english (7)


Year
From To Submit

2019 (1)

2018 (1)

2016 (3)

2015 (2)

-->