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Dementia, Frailty and Aging

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Book Series: Frontiers Research Topics ISSN: 16648714 ISBN: 9782889455232 Year: Pages: 121 DOI: 10.3389/978-2-88945-523-2 Language: English
Publisher: Frontiers Media SA
Subject: Medicine (General)
Added to DOAB on : 2019-01-23 14:53:42
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The number of older subjects is rapidly increasingly worldwide. As a consequence, the nature of clinical conditions is also changing. Traditional medicine and models of care have been based on the evaluation and treatment of single and usually acute conditions occurring in relatively young individuals. Today, the usual clinical manifestation of diseases is characterized by multiple and often chronic conditions affecting older people. In this scenario, frailty and dementia have been triggering special interest both in research and clinical settings due to their high prevalence, impact on the individual’s quality of life, and consequences for public health worldwide. These conditions aptly reflect the complexity of age-related pathological conditions, finding as causal factor a myriad of heterogeneous, interacting, and often still unclear pathophysiological processes. Indeed, their study is strongly affected by the difficulty to differentiate the effects of a normal aging process from eventual pathological deviations of the underlying systems. Their occurrence and trajectories over time are strongly affected by a wide array of factors and determinants that can be hardly attributed to the deficit/involvement of single biological systems and/or health domains. Moreover, environment and social factors also play a key role in the determination of phenotypes.The present Research Topic is aimed at widening our understanding of the frailty and dementia phenomena occurring with aging, in order to improve the clinical and public health approaches to these burdening conditions.

Dietary Protein and Muscle in Aging People

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ISBN: 9783038974574 9783038974581 Year: Pages: 160 DOI: 10.3390/books978-3-03897-458-1 Language: English
Publisher: MDPI - Multidisciplinary Digital Publishing Institute
Subject: Nutrition and Food Sciences
Added to DOAB on : 2019-02-14 10:56:39
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This Special Issue of Nutrients, entitled “Dietary Proteins and Muscle in Aging People”, welcomes the submission of manuscripts either reporting original research or reviewing the scientific literature. Manuscripts should focus on the mechanisms linking dietary protein with muscle quality and quantity. Articles presenting results from clinical trials testing protein interventions on muscle mass and function are welcome. The Special Issue aims at including articles spanning different disciplines to explore the topic of interest. Reports from basic to clinical and population research are suitable. Articles adopting a longitudinal approach or reporting data from life-long interventions/observations in the exploration of the theme will be given special consideration.Potential topics include, but are not limited to:•Description of patterns of dietary protein consumption across life•Influence of dietary protein intake on the functional status of older people•Preclinical and clinical studies describing the mechanisms through which protein intake modifies muscle mass and function•Protein/amino acid supplementation interventions against sarcopenia, cachexia, or disease conditions associated with muscle wasting in old age•Disease-specific alterations modifying the effects of dietary protein intake on skeletal muscles•Effects of the interactions of dietary protein intake and gut microbiota on skeletal muscles]

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