Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves
Abstract
Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF.
Keywords
atrial fibrillation; P-wave; Vorhof; electrophysiology; Computermodell; Elektrophysiologie; Vorhofflimmerncomputational modeling; atria; P-WelleISBN
9783731505280Publisher
KIT Scientific PublishingPublisher website
http://www.ksp.kit.edu/Publication date and place
2016Series
Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering,Classification
Technology: general issues